Extraosseous calcification in patients with chronic renal failure—no escape?
نویسندگان
چکیده
منابع مشابه
Extraosseous calcification in patients with chronic renal failure--no escape?
Paradigms provide frameworks for thinking about and describing the nature of reality. They allow us to infer causal relationships between observations, make predictions about future developments and, in the field of medicine, devise strategies for achieving therapeutic aims. Let me begin by following the advice of the geneticist Luigi Luca Cavalli-Sforza, who stated: ‘To understand the present,...
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In patients with chronic renal failure on regular dialysis treatment, limboconjunctival degenerations and calcifications are commonly observed. In this study three groups of patients were followed over a period of 6 years. The first group consisted of 47 patients with renal failure, the second group of 17 patients with renal failure and hyperparathyroidism not controlled by drugs, and the third...
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The mean bone pyrophosphate was 0.360 +/- 0.15 mg/g in 8 controls and 1.22 +/- 1.39 mg/g bone in 27 uremic patients (P less than 0.0025). 13 of the 27 uremic patients had bone pyrophosphate levels greater than 2 SD above control values. The ash content of uremic bones with increased pyrophosphate levels (group II) was 56 +/- 9% as compared to 64 +/- 2% in control bones (P less than 0.01) and 60...
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Accelerated atherosclerotic plaque calcification and extensive medial calcifications are common and highly detrimental complications of chronic kidney disease. Valid murine models have been developed to investigate both pathologically distinguishable complications, which allow for better insight into the cellular mechanisms underlying these vascular pathologies and evaluation of compounds that ...
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The prevalence and extent of vascular calcification (VC) increases rapidly with time on dialysis. There is increasing evidence that medial calcification of conduit arteries, without intimal disease, is associated with important abnormalities of vascular compliance and increased risk of cardiovascular death. Coronary artery calcification is also common in end-stage renal disease, but further res...
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ژورنال
عنوان ژورنال: Nephrology Dialysis Transplantation
سال: 2005
ISSN: 1460-2385,0931-0509
DOI: 10.1093/ndt/gfi030